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Presently preferred prokaryotic organisms for use herein include, but are not limited to Bacillus anthracis, Bacteriodes fragilis, Bordetella pertussis, Burkholderia cepacia, Camplyobacter jejuni, Chlamydia pneumoniae, Chlamydia trachomatus, Clostridium botulinum, Clostridum tetani, Clostridium perfringens, Clostridium difficile, Corynebacterium diptheriae, Enterobacter cloacae, Enterococcus faecalis, Escherichia coli, Haemophilus influenzae, Helicobacter pylori, Klebsiella pneumoniae, Listeria monocytogenes, Moraxella catarrhalis, Mycobacterium leprae, Mycobacterium tuberculosis, Neisseria gonorrhoeae, Nesseria meningitidis, Nocardia asteroides, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhi, Salmonella typhimurium, Shigella boydii, Shigella dysenteriae, Shigella flexneri, Shigella sonnei, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, Streptococcus pneumoniae, Treptonema pallidum, Vibrio cholerae, Vibrio parahemolyticus, and Yersina pestis. It has made numerous acquisitions, including Warner–Lambert in 2000, Pharmacia in 2003, and Wyeth in 2009 (the largest of the three at $68 billion)? The results of previous trials have been inconsistent?

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